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Insecticide resistance in mosquitoes: Development, mechanisms and monitoring

Authors:

Parakrama Karunaratne ,

University of Peradeniya, LK
About Parakrama
Department of Zoology
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Priyanka De Silva,

University of Peradeniya, LK
About Priyanka
Department of Zoology
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Thilini Weeraratne,

University of Peradeniya, LK
About Thilini
Department of Zoology
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Noble Surendran

University of Jaffna, LK
About Noble
Department of Zoology
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Abstract

Mosquito-borne diseases are of major public health concerns, mainly in tropical countries. Control of these diseases is primarily achieved through mosquito control. One of the major challenges encountered by mosquito control programmes is the development of resistance to insecticides by mosquitoes. Increased detoxifying activity through over expression of insect metabolic enzymes and altered target sites with decreased sensitivity to insecticides are the two major mechanisms of resistance. This review article presents our knowledge on development of insecticide resistance and the underlying biochemical and molecular mechanisms of resistance to major classes of insecticides. Techniques available to monitor resistance and to understand the underlying mechanisms are also discussed.
How to Cite: Karunaratne, P., De Silva, P., Weeraratne, T., & Surendran, N. (2018). Insecticide resistance in mosquitoes: Development, mechanisms and monitoring. Ceylon Journal of Science, 47(4), 299–309. DOI: http://doi.org/10.4038/cjs.v47i4.7547
Published on 05 Dec 2018.
Peer Reviewed

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